| Link | Phenotype | Citation | | 1 |
| oxidative stress resistance: decreased hydrogen peroxide (5 mM) | Auesukaree C, et al. (2009) Genome-wide identification of genes involved in tolerance to various environmental stresses in Saccharomyces cerevisiae. J Appl Genet 50(3):301-310 |
| 2 |
| affected redox environment - more oxidized cytosol "nil, tested DTT treatment" | Ayer A, et al. (2012) A genome-wide screen in yeast identifies specific oxidative stress genes required for the maintenance of sub-cellular redox homeostasis. PLoS One 7(9):e44278 |
| 3 |
| resistance to chemicals: decreased CTBT (4 ug/ml 7-chlorotetrazolo [5,1-c]benzo[1,2,4]triazine) no growth on YPD plus 4 ug/ml CTBT | Batova M, et al. (2010) Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine). BMC Genomics 11():153 |
| 4 |
| high susceptibility 1.2 or 1.5_mg/L mancozeb | Dias PJ, et al. (2010) Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach. OMICS 14(2):211-27 |
| 5 |
| resistance to chemicals: decreased S-{2-[4-(dihydroxyarsino)phenylamino]-2-oxoethyl}-glutathione | Dilda PJ, et al. (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47 |
| 6 |
| sensitive arsenic trioxide | Dilda PJ, et al. (2008) Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid. Int J Biochem Cell Biol 40(5):1016-29 |
| 7 |
| resistance (suppress the accumulation of mutations that inactivate the CAN1 gene canavanine | Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 |
| 8 |
| resistance to chemicals: decreased camptothecin (43 uM) | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 9 |
| resistance to chemicals: decreased cycloheximide (0.18 uM) | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 10 |
| resistance to chemicals: decreased hydroxyurea (100 mM) | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 11 |
| resistance to chemicals: decreased sirolimus (0.003 uM) sirolimus is rapamycin | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 12 |
| resistance to chemicals: decreased tunicamycin (0.6 uM) | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 13 |
| resistance to chemicals: increased fenpropimorph (16.5 uM) | Kapitzky L, et al. (2010) Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol 6():451 |
| 14 |
| Pointed strains alpha factor | Narayanaswamy R, et al. (2006) Systematic profiling of cellular phenotypes with spotted cell microarrays reveals mating-pheromone response genes. Genome Biol 7(1):R6 |
| 15 |
| resistance to chemicals: decreased L-1,4-dithiothreitol (16 mM) | Rand JD and Grant CM (2006) The thioredoxin system protects ribosomes against stress-induced aggregation. Mol Biol Cell 17(1):387-401 |
| 16 |
| resistance to chemicals: decreased cadmium dichloride (50 uM) | Serero A, et al. (2008) Yeast genes involved in cadmium tolerance: Identification of DNA replication as a target of cadmium toxicity. DNA Repair (Amst) 7(8):1262-75 |
| 17 |
| resistance to chemicals: decreased L-1,4-dithiothreitol (20 mM) | Tan SX, et al. (2009) Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell 20(5):1493-508 |
| 18 |
| resistance to chemicals: decreased tunicamycin (6 ug/ml) | Tan SX, et al. (2009) Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae. Mol Biol Cell 20(5):1493-508 |
| 19 |
| Sensitive Cumene Hydroperoxide | Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9 |
| 20 |
| Sensitive Diamide (thiol oxidizing agent) | Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9 |
| 21 |
| Sensitive Hydrogen Peroxide (H2O2) | Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9 |
| 22 |
| Sensitive Linoleic Acid 13Hydroperoxide | Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9 |
| 23 |
| resistance to chemicals: decreased acrolein (5 mM) | Trotter EW, et al. (2006) Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol 72(7):4885-92 |
| 24 |
| Sensitive Hydrogen Peroxide | Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24 |
| 25 |
| Sensitive Menadione | Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24 |