| Venn | A Citation / Phenotype | Intersection count | B Citation / Phenotype | p value | |
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 208 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 1.722e-184 |
|
| Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 199 | Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 1.432e-179 |
|
| Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
| 167 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 1.989e-149 |
|
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 143 | Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 7.87e-99 |
|
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 130 | Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
| 9.661e-97 |
|
| Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Lactic Acid
| 72 | Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
| 2.283e-95 |
|
| Citation Shuster A, et al. (2007) Alcohol-conferred hemolysis in yeast is a consequence of increased respiratory burden. FEMS Yeast Res 7(6):879-886
Phenotype MACH-Slowgrowers microbial alcohol conferred hemolysis
| 125 | Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 6.008e-95 |
|
| Citation Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Phenotype low Plasma Membrane Electron Transport Assay for PMET
| 78 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 5.643e-91 |
|
| Citation Ohya Y, et al. (2005) High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci U S A 102(52):19015-20
Phenotype morphological mutant 20 or more parameters disrupted with threshold 1.00E06
| 83 | Citation Watanabe M, et al. (2009) Comprehensive and quantitative analysis of yeast deletion mutants defective in apical and isotropic bud growth. Curr Genet 55(4):365-80
Phenotype bud morphology: abnormal bud is abnormally elongated
| 5.027e-84 |
|
| Citation Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9
Phenotype Sensitive Hydrogen Peroxide (H2O2)
| 88 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 3.337e-79 |
|
| Citation Jorgensen P, et al. (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297(5580):395-400
Phenotype cell size: increased mutant is among the largest 5% of haploid deletion strains
| 84 | Citation Ohya Y, et al. (2005) High-dimensional and large-scale phenotyping of yeast mutants. Proc Natl Acad Sci U S A 102(52):19015-20
Phenotype morphological mutant 20 or more parameters disrupted with threshold 1.00E06
| 6.046e-79 |
|
| Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
| 148 | Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 1.073e-76 |
|
| Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 165 | Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
| 3.346e-71 |
|
| Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype respiratory growth: absent glycerol
| 75 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 9.492e-71 |
|
| Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Hydrochloric Acid
| 65 | Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
| 8.966e-70 |
|
| Citation Dilda PJ, et al. (2005) Mechanism of selectivity of an angiogenesis inhibitor from screening a genome-wide set of Saccharomyces cerevisiae deletion strains. J Natl Cancer Inst 97(20):1539-47
Phenotype resistance to chemicals: decreased S-{2-[4-(dihydroxyarsino)phenylamino]-2-oxoethyl}-glutathione
| 72 | Citation Dilda PJ, et al. (2008) Insight into the selectivity of arsenic trioxide for acute promyelocytic leukemia cells by characterizing Saccharomyces cerevisiae deletion strains that are sensitive or resistant to the metalloid. Int J Biochem Cell Biol 40(5):1016-29
Phenotype sensitive arsenic trioxide
| 2.504e-69 |
|
| Citation Teixeira MC, et al. (2009) Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. Appl Environ Microbiol 75(18):5761-72
Phenotype resistance to chemicals: decreased ethanol (8%)
| 103 | Citation Dias PJ, et al. (2010) Insights into the mechanisms of toxicity and tolerance to the agricultural fungicide mancozeb in yeast, as suggested by a chemogenomic approach. OMICS 14(2):211-27
Phenotype high susceptibility 1.2 or 1.5_mg/L mancozeb
| 8.239e-68 |
|
| Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype mitochondrial morphology: abnormal morphology is somewhat affected; a fraction of cells exhibit wild-type mitochondrial morphology
| 66 | Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 4.505e-66 |
|
| Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Menadione
| 145 | Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
| 2.249e-64 |
|
| Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
| 204 | Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
| 4.232e-64 |
|
| Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Hydrogen Peroxide
| 142 | Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 2.632e-59 |
|
| Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Acetic Acid
| 75 | Citation Tucker CL and Fields S (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comp Funct Genomics 5(3):216-24
Phenotype Sensitive Ibuprofen
| 5.87e-57 |
|
| Citation Thorpe GW, et al. (2004) Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proc Natl Acad Sci U S A 101(17):6564-9
Phenotype Sensitive Hydrogen Peroxide (H2O2)
| 72 | Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 9.11e-57 |
|
| Citation Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95
Phenotype respiratory growth: absent glycerol carbon source
| 126 | Citation Yoshikawa K, et al. (2009) Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae. FEMS Yeast Res 9(1):32-44
Phenotype resistance to chemicals: decreased ethanol (8%)
| 2.486e-56 |
|
| Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 161 | Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
| 8.671e-55 |
|
| Citation Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90
Phenotype genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccha low dye binding (ldb) phenotype
| 75 | Citation Aouida M, et al. (2004) A genome-wide screen in Saccharomyces cerevisiae reveals altered transport as a mechanism of resistance to the anticancer drug bleomycin. Cancer Res 64(3):1102-9
Phenotype Sensitive to BLM Bleomycin (2.0 _g/ml)
| 1.061e-54 |
|
| Citation Kawahata M, et al. (2006) Yeast genes involved in response to lactic acid and acetic acid: acidic conditions caused by the organic acids in Saccharomyces cerevisiae cultures induce expression of intracellular metal metabolism genes regulated by Aft1p. FEMS Yeast Res 6(6):924-36
Phenotype Sensitivity to acids Acetic Acid
| 59 | Citation Suzuki T, et al. (2012) Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. J Biosci Bioeng 113(4):421-30
Phenotype hypersensitivity 4.0% llactic acid (pH 2.8)
| 1.788e-52 |
|
| Citation Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Phenotype respiratory growth: absent glycerol carbon source
| 75 | Citation McLaughlin JE, et al. (2009) A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin. Proc Natl Acad Sci U S A 106(51):21883-8
Phenotype resistance to chemicals: increased trichothecene (4 uM)
| 3.014e-52 |
|
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 58 | Citation Herst PM, et al. (2008) Plasma membrane electron transport in Saccharomyces cerevisiae depends on the presence of mitochondrial respiratory subunits. FEMS Yeast Res 8(6):897-905
Phenotype low Plasma Membrane Electron Transport Assay for PMET
| 4.187e-52 |
|
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 99 | Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype chemical compound excretion: increased glutathione SD medium
| 3.379e-51 |
|
| Citation Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42
Phenotype chemical compound accumulation: decreased glycogen
| 150 | Citation Yoshikawa K, et al. (2011) Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae. Yeast 28(5):349-61
Phenotype vegetative growth: decreased rate nil
| 6.337e-51 |
|
| Citation Bonangelino CJ, et al. (2002) Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Mol Biol Cell 13(7):2486-501
Phenotype secreted strong-to-moderate levels of carboxypeptidase Y Screen for secretion of CPY into the medium
| 71 | Citation Perrone GG, et al. (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Phenotype chemical compound excretion: increased glutathione SD medium
| 9.553e-51 |